Pregabalin Oral Route Side Effects In addition to the uses listed above, Lyrica may also be used off-label for other conditions. In one 13-week clinical trial, people rated their pain on an 11-point scale before starting treatment. To be eligible for the trial, people had to have had shingles at least 3 months before and have a pain score of at least 4. They were also allowed to take acetaminophen for...